Non-denatured collagen type Ⅱ (undenatured type Ⅱ Collagen, UCⅡ) InterHealth companies in the United States for 10 years time, from discovery to patent the process to extract them (with a patented low-temperature extraction process, in order to output invariance type II collagen protein), and then after dogs, horses and other large animals, experiments confirm the effectiveness of human double-blind study to confirm the effectiveness of the US food safety certification (GRAS), and then to the United States food and Drug safety Agency (FDA) certification for the new line in the official journal of food ingredients (NDI), all the way hard way, is to prove that the material is safe and effective. Non-denatured type II collagen can inhibit joint inflammation is the culprit, there is collagen-specific immune T cells (collagen-specific Fell, C-ST cells) does not start, it does not cause inflammation, pain self can removal, removal of the pain is to remove the root cause, rather than just blocking the pain analgesics, but inflammation continues, more and more serious illnesses like. So just have to let the joint recuperate, cartilage restoration, and to let us in motility, mobile power, flexibility, satisfactory improvement in all aspects. In the use of non-denatured collagen type Ⅱ on arthritis, in addition to the effective removal of joint inflammation, and let the most disturbing long-term pain relief and sustained improvement, but in sustained remission of inflammation and pain, knee flexible activities degree also obtained substantial improvement.